5-MeO-DMT is endogenous to the human organism and when spontaneously arising is likely the trigger for the mystical experience. Integrating external peak experiences of 5-meO then can be seen as entrainment for the in-built mystical potential. Can modalities like yoga, meditation, breath work etc. prepare, entrain and extend the divine relationship? Is integration of the 5-MeO experience more akin to an upgrade of the human-divine relationship?